There is nothing that will happen that isn't already known by God. Everything molecular, every single molecule has a designated time, and space for it's purpose.
If it were any other way you open the door for chance. Where there is possibility for chance, you can not have perfect order, which gives chaos opportunity.
In a system where you have both molecular and non-molecular creations affecting each other, i see absolutely no other way of sustaining itself as a prospering creation than to have a certain time, space and purpose for everything.
Now we get to throw the glory of God on the cake to make it just how he wants it, and I highly doubt the good Lord is going to roll the dice and take a chance with his glory, and that includes leaving any part of his will to the decision of an imperfect, finite, sinful being.
That's how I see it.