My brothers and sisters in Jesus Christ, you have to remember:
And when ye shall see Jerusalem compassed with armies, then know that the desolation thereof is nigh. Then let them which are in Judaea flee to the mountains; and let them which are in the midst of it depart out; and let not them that are in the countries enter thereinto. Luke 21:20,21
It is during this time, that this will happen:
For the days shall come upon thee, that thine enemies shall cast a trench about thee, and compass thee round, and keep thee in on every side, And shall lay thee even with the ground, and thy children within thee; and they shall not leave in thee one stone upon another; because thou knewest not the time of thy visitation. Luke 19:43,44
So understand, during the 3 1/2 year tribulation (Revelation 13:5), "they shall not leave in thee one stone upon another" (Luke 19:44) - talking about Jerusalem.
And remember, the temple from Ezekiel Chapters 40 - 48 is about to be built on the southwest corner of the Temple Mount, in its place - directly above the first temple that is buried (1 Kings 9:7, 2 Chronicles 7:20) deep under the dirt (Jeremiah 9:11) and "rubbish" (Nehemiah 4:2) on "mount Moriah" (2 Chronicles 3:1). Zion is currently located south of the Temple Mount, in the city of David (2 Samuel 5:7, 1 Kings 8:1). But Zion was given the command:
O Zion, that bringest good tidings, get thee up into the high mountain; O Jerusalem, that bringest good tidings, lift up thy voice with strength; lift it up, be not afraid; say unto the cities of Judah, Behold your God! Isaiah 40:9
That means for Zion to physically move its location, "up into the high mountain" (Isaiah 40:9), from where it is. So when the Lord (Romans 11:28, 1 Corinthians 12:27) begins to build up Zion (Psalms 102:16) - the third temple begins to be built, it will physically have moved its place from where it is currently, "up into the high mountain" (Isaiah 40:9) - "mount Zion" (Psalms 125:1).
And Zion is inside of Jerusalem, but not a part of it (Isaiah 2:3, Micah 4:2), as they are two separate places. So when the word of God says that "they shall not leave in thee one stone upon another" (Luke 19:44) - again, talking about Jerusalem, that does not mean every stone inside the boundary of Jerusalem, as Zion is separate from Jerusalem, within it. It is written what is going to happen to the outer court of the temple that is about to be built, during the tribulation (Revelation 11:2), but they will not destroy the temple. Our Lord Jesus Christ will come (Revelation 19:11-21, Isaiah 31:4, Ezekiel 43:1-7) and reign from that temple for 1,000 years (Revelation 20:4).
The 3 1/2 year tribulation (2 Thessalonians 2:4, Daniel 7:21, Matthew 24:15-28, Mark 13:14-23, Luke 21:20-24, Ezekiel 8:3,5, Revelation 13:15-17) will be preceded by 3 1/2 years (Revelation 11:3) of daily animal sacrifice on the temple altar (Daniel 9:27, Ezekiel 40:47). And it will be followed by 30 days after it (Matthew 24:29, Mark 13:24,25, Luke 21:25,26, Revelation 16:1-16). And in the 45 days after that (Matthew 24:36, Daniel 12:11,12), our Lord and Savior Jesus Christ will come back (Isaiah 27:13, Luke 18:8).
So if you are in Judaea during the start of the tribulation, you need to flee to "the mountains" (Matthew 24:16, Mark 13:14, Luke 21:21). Because remember, one stone shall not be left "upon another" (Luke 19:44) in Jerusalem.
Glory to God.