2Th 2:4
Who opposeth and exalteth himself above all that is called God, or that is worshipped; so that he as God sitteth in the temple of God, shewing himself that he is God.
Nobody can possibly evade the 70th week of Daniel references here.
And NO, this cannot refer to the long past events of Antiochus IV Epiphanes, who was but a type of a real person desecrating the real Temple in a real Jerusalem.
Jesus of course validates Daniel's prophecies as being the future 70th week time of Jacobs trouble aka the great tribulation.
I don't think anyone in this thread has yet suggested that the man in 2Thes2 is Epiph. IV.
There is however a passage in Daniel 11 that is most definitely him.
Here it is:
21 And in his estate shall stand up a vile person, to whom they shall not give the honour of the kingdom: but he shall come in peaceably, and obtain the kingdom by flatteries.
22 And with the arms of a flood shall they be overflown from before him, and shall be broken; yea, also the prince of the covenant.
23 And after the league made with him he shall work deceitfully: for he shall come up, and shall become strong with a small people.
24 He shall enter peaceably even upon the fattest places of the province; and he shall do that which his fathers have not done, nor his fathers' fathers; he shall scatter among them the prey, and spoil, and riches: yea, and he shall forecast his devices against the strong holds, even for a time.
25 And he shall stir up his power and his courage against the king of the south with a great army; and the king of the south shall be stirred up to battle with a very great and mighty army; but he shall not stand: for they shall forecast devices against him.
26 Yea, they that feed of the portion of his meat shall destroy him, and his army shall overflow: and many shall fall down slain.
27 And both of these kings' hearts shall be to do mischief, and they shall speak lies at one table; but it shall not prosper: for yet the end shall be at the time appointed.
28 Then shall he return into his land with great riches; and his heart shall be against the holy covenant; and he shall do exploits, and return to his own land.
29 At the time appointed he shall return, and come toward the south; but it shall not be as the former, or as the latter.
30 For the ships of Chittim shall come against him: therefore he shall be grieved, and return, and have indignation against the holy covenant: so shall he do; he shall even return, and have intelligence with them that forsake the holy covenant.
31 And arms shall stand on his part, and they shall pollute the sanctuary of strength, and shall take away the daily sacrifice, and they shall place the abomination that maketh desolate.
Compare to an account of Antiochus IV Epiphanes by secular historians:
en.wikipedia.org
Notice that Antiochus IV=king of the north, and that King Ptolemy VI Philometor=king of the south.
former kings of the north in the Seleucid Dynasty are describes in the previous verses of Ch.11.
Notice also that some secular historians think that they have discovered "proof" that ch.7-14 of Daniel was written after the time of Antiochus IV, because the description is so accurate.