Some would say she is Rome.
The Great Babylon is referred to as "the great city" -- split into 3 parts -- Washington DC, NY and Rome. We hear of the "mother of harlots" that would include London, the US is the daughter.
Revelation 17:1 "she sits by many waters" -- Rome is not on "many waters". This could refer to the British empire (the mother) and the US.
"All the nations have drunk the maddening wine of her adulteries" -- Clearly could refer to Rome (religious Babylon) and the US (commercial Babylon) and London (imperialism)
The kings of the earth committed adultery with her (could refer to all three: Rome, London and Washington DC).
The merchants of the earth grew rich from her excessive luxuries -- currently that can only refer to Washington DC.
Pay her back double -- could be a reference to the Catholic church (religious Babylon) or to the CIA (commercial Babylon).
Woe to you mighty city of Babylon -- No way that is currently referring to Rome or London. Could only be a reference to Washinton DC
The merchants of the earth will weep and mourn over her because no one buys their cargo anymore -- Clearly must be a reference to the US
Babylon a land of merchants -- all of these multinational corporations like Coca Cola and McDonalds, they are not from Rome or London.
Babylon has a gold cup filled with the wine of her adulteries -- What nation had the Bible, the word that is considered fine gold, that they sent throughout the entire world and at the same time has filled that cup with the falsehoods of hollywood, the wine of adultery?