You need your own computer, and desk and preferably a room of your own that is separate as your 'office'. Depends what you want to do, join a company that lets your work from home or become self employed.
If you are self employed it might be harder because you have to set it all up yourself, pay all taxes, and work all hours to break even. But the upside is you call all the shots, make all the decisions etc. However getting word of mouth put to clients will be on you as nobody else will know what you do unless you tell them. so it will be a lot of online hustling. You might need a separate phone line and bank accounts etc.
if you dont want to do computer work you can...do catering, using your kitchen, do sewing (if you have a machine) hairdressing (you can set up a home salon) grow plants (need your own shed) or create art (need your own studio) teach ( set up your own homeschool or day care)
you can use your garage as a workshop. But depends on how big your garage is. You might actually want to park your car in there!
Or if you have spare bedrooms operate a B&B esp if its in a good location, and host students and guests.
I think the downside to working from home is you might then never go out and see people lol.