One variable would be whether it is a live vaccine or dead. If it is live, anyone who is immune-suppressed will most likely contract the disease. Also it depends if it is done in an egg culture as people with egg allergies may have severe, possibly fatal reactions.
The Moderna vaccine is a mRNA vaccine it is genetically coded to create the protein that our immune system uses to defeat the virus ability to infect our cells. There is no virus, dead or alive, nor any gentic parts or antigens from the virus injected. It is really rather amazing and has promise for curing certain kinds of cancer. It has already cured certain melenoma cancers by genetically coded mRNA that produces proteins designed specifically to stop the melenoma cancer cells in individual persons. Like a personalized custom cancer cure just for them.
The one from Oxford is also a protein using Chimpanzee cells and I have not read the details about how it works. I know that there are many vaccines being developed world wide and some are using the traditional methods and I have not heard about what level of success they are reporting.
Obviously the US government is convinced that the the Oxford Pfyzer and Moderna vaccines will work because they have already authorized billions of doses to be manufactured even though 3 phase testing of 30-40K patients just started. They are already confident based on Phase 2 success and are spending the money ahead of time.
I have also read that none of the safety testing is being skipped that they have been doing for decades. The speeding up process is all related to removing a myriad of bottlenecks that were unnecessary levels of waiting for approvals and just people not doing their jobs so that the whole process waits months over a step that takes a few days. Things like that do not jeopardize safety they simply improve the process and hopefully save thousands of lives by getting the vaccine out there so people can get it in time.
I just noticed that you can change your vote in the poll. I wonder if anyone will change their vote during the life of this thread based on the information that is posted by the posters? This should be interesting.