This may sound harsh, but I honestly believe that the confusion and lack of understanding of which she spoke only comes to those who either haven't heard the true gospel message or to those who have heard it, but haven't truly responded to it in their hearts.
Jesus said that we cannot be his disciples unless we deny ourselves, take up our crosses, and follow him. He also said that we must lose our lives to find them. So, yes, it's definitely a matter of God's will being done in and through our lives as opposed to us seeking to fulfill our own lusts or desires.
Simply put, we were created by God and for God. We all went astray as lost sheep, and Jesus Christ, the good shepherd, came to seek and to save us who were lost. That salvation is a reconciling of ourselves back unto God in order for us to fulfill the purposes for which we were actually created in the first place. If we understand this, then there's really no need for much of the heartbreaks which we face, which are often nothing more than us not getting our selfish desires fulfilled. Our real heartaches should be in relation to seeing the lost perishing all around us, but many people seem to have no real regard for them whatsoever. These are just general observations of mine, and not direct accusations against anybody here in particular.
Revelation 4:11
Thou art worthy, O Lord, to receive glory and honour and power: for thou hast created all things, and for thy pleasure they are and were created.