First of all, how about the simple and basic doctrine of the infallibility of the Bible? That's the most important doctrine of them all. Can God's word be trusted, every word? It's the whole foundation of everything God has revealed to us about Himself and what we believe about our Redeemer and Lord and Saviour Jesus Christ. He either told us the truth when He said that heaven and earth shall pass away but His words would not pass away, or He lied to us and cannot be trusted. You pick which option you are going to believe.
Is the Jesus Christ in your Bible the one who lied in John 7:8 as the NASB, ESV, St. Joseph NAB, New Jerusalem bible read? That would go against the most important doctrine of all. The validity of God's word.
John 7:8-10 Here we read of Jesus telling his brethren to go up unto a feast and He says: "I go NOT up YET unto this feast; for my time is not yet full come. When he had said these words unto them, he abode still in Gallilee. But when his brethren were gone up, then went he also up unto the feast, not openly, but as it were in secret." He did in fact go up to the feast.
Vaticanus, as well as P66, 75, and the majority of all texts read as does the KJB with: "I go not up YET unto this feast", and so do the Revised Version 1881, Geneva, Tyndale, Bishops', Coverdale, the NIV, Holman Standard, the 2005 ISV (International Standard Version), Young, Weymouth, Rotherham's Emphasized Bible 1902.
However Sinaiticus says: "I DO NOT GO to this feast", and so do the NASB, ASV, RSV, ESV , Catholic St. Joseph NAB, New Jerusalem bible 1985, and Wallace's NET version thus making our Lord a liar. The nature of this so called "science" is also seen in that Westcott and Hort originally read "NOT YET" and so did the previous Nestle-Aland critical texts up until a few years ago. But the more recent ones have "scientifically" changed to now read "I do NOT go to this feast."
The Vaticanus and Sinaiticus differ thousand of times, and these are the "trusted" manuscripts of the new age versions.