The Bible does speak to the fact that some people will harden their hearts to the point of searing their own conscience, but these people will never desire to repent or be changed. God knows that many will reject Him and never turn to Him, but whosoever desires to come may come.
Romans 1:21
“Because that, when they knew God, they glorified him not as God, neither were thankful; but became vain in their imaginations, and their foolish heart was darkened.”
They chose their own path. Dark hearts do not seek the Lord.
One should never ignore the times when Jesus knocks on the door of you heart. Is Jesus knocking on your door now? If so, open it immediately. One never knows if this day might be their last.
Revelation 3:20
“Behold, I stand at the door, and knock: if any man hear my voice, and open the door, I will come in to him, and will sup with him, and he with me.”