This is the definition of “defile” in this passage:
5351. phtheiró ►
Strong's Concordance
phtheiró: to destroy, corrupt, spoil
Original Word: φθείρω
Part of Speech: Verb
Transliteration: phtheiró
Phonetic Spelling: (fthi'-ro)
Definition: to destroy, corrupt, spoil
Usage: I corrupt, spoil, destroy, ruin.
Corrupting your body (temple) carries some harsh penalties. If altering your genetic makeup doesn’t qualify as corrupting God’s creation, I don’t know what does:
1 Corinthians 3:16-18
New King James Version
16 Do you not know that you are the temple of God and that the Spirit of God dwells in you? 17 If anyone defiles the temple of God, God will destroy him. For the temple of God is holy, which temple you are.
Avoid Worldly Wisdom
18 Let no one deceive himself. If anyone among you seems to be wise in this age, let him become a fool that he may become wise.